Randomised controlled trial comparing hypnotherapy versus gabapentin for the treatment of hot flashes in breast cancer survivors: a pilot study — MacLaughlan David et al. 3 (9) — BMJ Open

Hypnotherapy and gabapentin demonstrate efficacy in improving hot flashes. A definitive trial evaluating traditional interventions against CAM methods is feasible, but not without challenges. Further studies aimed at defining evidence-based recommendations for CAM are necessary.

via Randomised controlled trial comparing hypnotherapy versus gabapentin for the treatment of hot flashes in breast cancer survivors: a pilot study — MacLaughlan David et al. 3 (9) — BMJ Open.

Physical activity and quality of life in breast cancer survivors: the role of self-efficacy and health status – Phillips – 2013 – Psycho-Oncology – Wiley Online Library

Physical activity may influence QOL in breast cancer survivors through more proximal, modifiable factors.

via Physical activity and quality of life in breast cancer survivors: the role of self-efficacy and health status – Phillips – 2013 – Psycho-Oncology – Wiley Online Library.

Access : |[lsquo]|Being there|[rsquo]| for women with metastatic breast cancer: a pan-European patient survey : British Journal of Cancer

These findings show a continuing need to provide women with advanced breast cancer with better information and emphasise the importance that these patients often place on prolonging survival.

via Access : |[lsquo]|Being there|[rsquo]| for women with metastatic breast cancer: a pan-European patient survey : British Journal of Cancer.

Supportive care during treatment for breast cancer: Resource allocations in low- and middle-income countries. A Breast Health Global Initiative 2013 consensus statement

This consensus statement describes twelve key recommendations for supportive care during treatment in low- and middle-income countries, identified by an expert international panel as part of the 5th Breast Health Global Initiative (BHGI) Global Summit for Supportive Care, which was held in October 2012, in Vienna, Austria.

via Supportive care during treatment for breast cancer: Resource allocations in low- and middle-income countries. A Breast Health Global Initiative 2013 consensus statement.

The evolution of psychological distress trajectories in women diagnosed with advanced breast cancer: a longitudinal study – Lam – 2013 – Psycho-Oncology – Wiley Online Library

Most women with ABC did not experience psychological distress over 12 months following diagnosis of ABC. Preventive interventions should focus on women at risk of high persistent distress and reducing rumination, providing emotional support, and managing physical symptoms.

via The evolution of psychological distress trajectories in women diagnosed with advanced breast cancer: a longitudinal study – Lam – 2013 – Psycho-Oncology – Wiley Online Library.

Utilization of intravenous bisphosphonates in patients with bone metastases secondary to breast, lung, or prostate cancer – Online First – Springer

IVBs are used more frequently in patients with BMets secondary to BC than PC or LC. Many patients interrupt or discontinue IVB therapy within 12 months of initiation potentially impacting effectiveness.

via Utilization of intravenous bisphosphonates in patients with bone metastases secondary to breast, lung, or prostate cancer – Online First – Springer.

Randomized Controlled Trial of Mindfulness-Based Cancer Recovery Versus Supportive Expressive Group Therapy for Distressed Survivors of Breast Cancer (MINDSET)

Conclusion In the largest trial to date, MBCR was superior for improving a range of psychological outcomes for distressed survivors of breast cancer. Both SET and MBCR also resulted in more normative diurnal cortisol profiles than the control condition. The clinical implications of this finding require further investigation.

via Randomized Controlled Trial of Mindfulness-Based Cancer Recovery Versus Supportive Expressive Group Therapy for Distressed Survivors of Breast Cancer (MINDSET).

Attitudes of young patients with breast cancer toward fertility loss related to adjuvant systemic therapies. EORTC study 10002 BIG 3-98 – Senkus – 2013 – Psycho-Oncology – Wiley Online Library

For the majority of young patients with breast cancer, cure remains their first priority; for this, they are willing to accept a considerable decrease in future fertility, and only less than 10% will forego chances of cure to preserve fertility. Copyright © 2013 John Wiley & Sons, Ltd.

via Attitudes of young patients with breast cancer toward fertility loss related to adjuvant systemic therapies. EORTC study 10002 BIG 3-98 – Senkus – 2013 – Psycho-Oncology – Wiley Online Library.

A prospective, multicenter validation study of a prognostic index composed of S-phase fraction, progesterone receptor status, and tumour size predicts survival in node-negative breast cancer patients: NNBC, the node-negative breast cancer trial

Conclusions This prospective study validates a prognostic index consisting of a proliferation factor, PR-status, and tumour size. The index may be helpful for prognostic considerations and for selection of patients in need of adjuvant therapy.

via A prospective, multicenter validation study of a prognostic index composed of S-phase fraction, progesterone receptor status, and tumour size predicts survival in node-negative breast cancer patients: NNBC, the node-negative breast cancer trial.

SpringerPlus | Abstract | Trade-offs in quality of life and survival with chemotherapy for advanced breast cancer: mature results of a randomized trial comparing single-agent mitoxantrone with combination cyclophosphamide, methotrexate, 5-fluorouracil and prednisone

Despite the greater toxicity, the superior antitumor activity of CMFP led to an overall improvement in quality-adjusted PFS. In advanced breast cancer, in clinical decision making about treatment for palliative intent, the principle used to assess trade-offs between antitumor efficacy and toxicity remains relevant and applicable to all modern therapeutic agents.

via SpringerPlus | Abstract | Trade-offs in quality of life and survival with chemotherapy for advanced breast cancer: mature results of a randomized trial comparing single-agent mitoxantrone with combination cyclophosphamide, methotrexate, 5-fluorouracil and prednisone.