Long-acting bronchodilators improve Health Related Quality of Life in patients with COPD

The data coming from the review support the efficacy of long acting bronchodilators in improving HRQoL/HS of COPD patients. Further research evaluating HRQoL/HS as primary outcome and according to guidelines on Patient Reported Outcomes is needed.

via Long-acting bronchodilators improve Health Related Quality of Life in patients with COPD.

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A post hoc pooled analysis of exacerbations among US participants in randomized controlled trials of tiotropium

Tiotropium significantly reduced the risk and rates of exacerbations and hospitalizations among US patients with COPD.

via A post hoc pooled analysis of exacerbations among US participants in randomized controlled trials of tiotropium.

The effects of Provent on moderate to severe obstructive sleep apnoea during continuous positive airway pressure therapy withdrawal: a randomised controlled trial — Rossi et al. 68 (9): 854 — Thorax

Conclusions Provent cannot be recommended as an alternative short-term therapy for patients with moderate to severe OSA already on CPAP.

via The effects of Provent on moderate to severe obstructive sleep apnoea during continuous positive airway pressure therapy withdrawal: a randomised controlled trial — Rossi et al. 68 (9): 854 — Thorax.

The Pharmacological Approach to the Elderly COPD Patient – Springer

International treatment guidelines to reduce symptoms and reduce the risk of acute exacerbations exist. Relief of dyspnea and control of anxiety are important. The approach to each patient is best individualized. Earlier use of palliative care should be considered when traditional pharmacotherapy fails to achieve outcome measures and before consideration of end-of-life issues.

via The Pharmacological Approach to the Elderly COPD Patient – Springer.

Annals of Internal Medicine | Review: Inhaled medications vary substantively in their effects on mortality in COPD

Annals of Internal Medicine | Review: Inhaled medications vary substantively in their effects on mortality in COPD.