The expanding armamentarium of drugs to aid sputum clearance… : Current Opinion in Pulmonary Medicine

Dornase alfa, a mucolytic agent, and hypertonic saline and mannitol, both hyperosmolar agents, have all been shown to benefit patients with cystic fibrosis. The optimal combination of therapies has not been identified, but a combination of a hyperosmolar agent combined with a mucolytic provides the most logical approach to improving lung function and reducing exacerbations.

via The expanding armamentarium of drugs to aid sputum clearance… : Current Opinion in Pulmonary Medicine.

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