A Systematic Review of the Demoralization Syndrome in Individuals with Progressive Disease and Cancer: A Decade of Research

Overall, this systematic review was limited by the extent of variability in the characteristics of studies. Patients who are single, isolated or jobless, have poorly controlled physical symptoms, or have inadequately treated anxiety and depressive disorders are at increased risk for demoralization. Clinical recognition of demoralization can trigger more focused interventions.

via A Systematic Review of the Demoralization Syndrome in Individuals with Progressive Disease and Cancer: A Decade of Research.

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